The demand for immune health support is on the rise; however, the complexity of the immune system challenges formulators to address both the adaptive and innate systems for an adaptogenic approach to a balanced immune response. Tinospora cordifolia is founded in Ayurvedic medicine and used for historically to offer balancing, rejuvenating properties through polysaccharides and polyphenols. This combination works through several primary actions; by regulating several immune mediators to stimulate the activity of white blood cells such as macrophages, reducing the number of histamine-containing eosinophil, and by modulating oxidative stress.