UC-II®, an abbreviation of undenatured type II collagen, is an ingredient that enables the development of dosage forms that are smaller and are taken less frequently than the alternatives. The joint health supplement sector has traditionally been a productivity and profitability powerhouse. Retailers and supplement manufacturers have watched metrics for the high-ring segment go up for years. Yet recently the trend has reversed. Now, amid fears that the sector is in permanent decline, mounting data suggest that the salvation of joint health may lie in an ingredient: UC-II®.