Fish bone powder ingredient six times more absorbable than calcium carbonate

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A natural form of calcium hydroxyapatite used by Hosfeth in their CalGo supplement comes directly from Atlantic salmon and is six times more absorbable than calcium carbonate, a study has found.

New research has highlighted the positive effect of Hofseth BioCare’s collagenic bone powder ingredient in sustaining bone health which was published in the Biomedical Journal of Scientific & Technical Research. 

The company uses patent-protected hydrolysis technology to convert fresh sashimi-grade salmon byproducts into nutritional ingredients for the enhancement of human health.

They say this latest discovery presents game-changing opportunities for nutraceutical manufacturers seeking to innovate in the bone health market with natural, sustainable and effective ingredients. 

The randomised, double-blind crossover study was designed to investigate the serum level of calcium in 12 healthy postmenopausal woman 24 hours after a single dose of CalGo.

The study found a higher availability of serum calcium suggesting this natural form of bone calcium is more easily absorbed by the gastrointestinal tract – six times more than standard calcium carbonate supplementation.

Elemental calcium

The researchers noted that traditional supplementation with non-hydroxyapatite calcium salts has focused on delivering high levels of elemental calcium but that this had resulted in a limited impact on bone density and strength.

They wrote: "In summary, CalGo is derived from the off-cuts of salmon fillet production thereby utilising fish bones which would previously have been discarded as a waste product.

"This study builds further on the profile of this sustainable resource for the benefit of health. The findings in the present study suggest that bone meal from Norwegian Atlantic salmon is easily absorbed by the body and combined with previous data which indicated a potential to increase bone formation, CalGo looks to be a promising ingredient for supplementation to sustain bone health."

The researchers said the findings, when combined with previous data indicating a potential to increase bone formation, point to the superior efficacy of CalGo in delivering complete bone matrix support, from better cartilage function and joint health to increased bone strength and density.

Salmon off-cuts

The publication of the study further builds on the profile of the underutilised salmon off-cuts as a sustainable, zero-waste resource for optimal nutritional performance. 

"At Hofseth BioCare, we understand fresh thinking is crucial to progression and we remain steadfast in our mission to forge a new era in nutrition – one that is sustainable, traceable and most importantly, evidenced and effective,” said Dr Crawford Currie, Head of Medical R&D at Hofseth BioCare.

“These findings strengthen a growing body of evidence that CalGo™ is a promising ingredient in sustaining bone health, with both preventative and remedial benefits.

"Further clinical research studies are ongoing and we are excited to discover the full potential of our naturally-inspired nutritional innovations.”

Source: Biomedical 

First published: DOI10.26717/BJSTR.2022.41.006583

A Randomized, Blinded, Calcium-Carbonate Controlled Cross Over Study of Serum Calcium Levels 24 Hours After CalGotm Oral Supplementation in Post- Menopausal Women

Authors: Crawford Currie et al