Patents have been obtained by Nektium for Zynamite as an ingredient for enhancing brain activity in all major international markets. These patents refer to Zynamite’s ability to improve alertness, concentration, and memory. In some countries it also includes additional effects, such as its use as an ingredient for enhancing mood, reducing stress, and as a replacement for caffeine.
A study of the leaves found the most active biological constituent of MLs is mangiferin, followed by phenolic acids, benzophenones, and other antioxidants such as flavonoids, carotenoids, quercetin, isoquercetin, ascorbic acid, and tocopherols. Mangiferin is the main contributor of most of the biological activities of mabgo leaves extract.
The study also found that mango leaves are the potential source of minerals, nitrogen, potassium, phosphorus, iron, sodium, calcium, magnesium, and vitamins, viz. A, B, E, and C. A major bio-macromolecule present in mango leaves is protein.
Brain activity
Further patent applications for Zynamite linked to sports performance are currently under review to complement the existing patents in the field of cognition, reinforcing the exciting value proposition of Zynamite®.
Thomas Adler, Chief Business Officer at Nektium, said: “We are delighted to have several patents in place for Zynamite® because it supports what we have achieved so far with this ingredient, and it confirms the innovative character of the product and of Nektium as an organization.”
He continued: “Zynamite is a unique product which has been formulated to deliver both mental and physical energy, and this has been verified by human trials, publications and now, several patent families. Supplement and functional food manufacturers can be reassured by these patents, which support the claims about Zynamite’s beneficial effects on human health.”
The researchers in the study found that the leaves exhibit exceptional biological, medicinal, and metabolic properties.
They wrote: "Mango leaves are otherwise considered as a waste material generated mainly through the pruning of mango plants; in reality, they are a most significant resource containing a wide variety of bioactive compounds (phenolics and essential oils), crude protein, dietary fiber, minerals, and vitamins."
They noted that the various bioactive compounds present in the leaves include phenolic compounds, flavonoids, benzophenones, sesquiterpenes, saponins, xanthones, tannins, terpenoids, and alkaloids.
Their extract, they said, is found useful for the treatment of common diseases like diarrhea, chronic ailments like diabetes, and fatty liver disease.
They found that the extracts of the leaves are also crucial in as an anti-obesity agent and demonstrate hepatoprotective action.
Vital chemical compounds
The added: "There are numerous vital chemical compounds present in mango leaves, which are instrumental to performing various metabolic, bacteriostatic, and antimicrobial activities. Some of these include gurjunene, trans-caryophyllene, humulene, selinene, and so on."
They said mangiferin present in mango leaves was also found to mitigate the oxidative stress involved in the treatment of numerous pathologies.
They concluded: "Mango leaves are thus a potential source of cost-effective food supplements and nutritive ingredients for improving human health and curing acute and chronic diseases."
Source: Nektium/PubMed
Published: doi.org/10.3390/antiox10020299
Mango (Mangifera indica L.) Leaves: Nutritional Composition, Phytochemical Profile, and Health-Promoting Bioactivities
Author: Manoj Kumar et al