Scientists from DuPont Nutrition & Health and the University of Oxford report in Nutrients that the company’s Litesse polydextrose, part of the DuPont Danisco range, are associated with reductions in calorie intake when consumed at levels of 6.25-25g in a mid-morning snack.
This meta-analysis was based on data from seven acute or chronic, randomized, and used placebo-controlled nutritional interventions. Polydextrose was consumed either alone (including as supplements) or in combination with other foods.
“This review demonstrates, for the first time, that polydextrose reduces the Desire to Eat during the Satiation period,” wrote the researchers, led by Dr Alvin Ibarra, senior scientist and member of the DuPont Nutrition & Health review team.
“This effect was also significant in the sub-analysis by sex for the male population. The results on this subjective feeling of appetite may explain, at least in part, the observed effects of polydextrose on the reduction of energy intake at a subsequent meal. There were no differences on Hunger, Satisfaction, or Fullness during the Satiation or Satiety periods.”
Commenting separately, Dr Ibarra said: “In addition, we have seen that this reduction in calorie intake is not compensated for during the rest of the day and may play a role in reducing total daily calorie intake significantly.”
Impact on appetite
Another meta-analysis examined the potential of the Litesse polydextrose ingredient to modulate subjective appetite ratings.
Data from six trials were included in the meta-analysis, published in Appetite, which found that the ingredient could have a positive effect on appetite ratings.
“This shows that Litesse is able to reduce the desire to eat immediately after a meal which includes Litesse,” said Dr Ibarra. “There is also a trend towards reduced hunger and increased satisfaction between meals after the consumption of Litesse.
“This means that Litesse represents a very exciting opportunity for our customers who wish to develop their weight management products with satiety enhancing and appetite reduction qualities. Our customer applying Litesse to their own brands can now help consumers reduce their caloric consumption and help them meet their weight-management goals.”
A new methodology for measuring changes in appetite
Making a meaningful comparison of results obtained from widely differing criteria for studies of appetite ratings was the biggest challenge for the authors, and they developed a new methodology for estimating changes in appetite before and after a meal.
“We are now using this new methodology to analyze the appetite rating results during the satiation and satiety periods with a positive acceptance from the scientific community,” said Dr Ibarra.
Sources:
2016, 8(1), 45; doi:10.3390/nu8010045
“Effect of Polydextrose on Subjective Feelings of Appetite during the Satiation and Satiety Periods. A Systematic Review and Meta-Analysis”
Authors: Ibarra A, Astbury NM, Olli K, Alhoniemi E, Tiihonen K
2015, Volume 87, Pages 30–37
“Effects of Polydextrose on Different Levels of Energy Intake: A Systematic Review and Meta-Analysis”
Authors: Ibarra A, Astbury NM, Olli K, Alhoniemi E, Tiihonen K