Fuji targets excipients expertise at nutra industry

By Mike Stones

- Last updated on GMT

Pharmaceutical company Fuji Health Science is bringing its expertise with functional excipients to the dietary supplement industry, with a rapid disintegration technology.

The company has applied its experience of functional excipients with applications that go beyond non-active filler or binder to supplements with the launch of F-Melt and Fujicalin.

Candidates for the technology include CoQ10 and vitamin B12, the company said.

F-Melt is a proprietary excipient system designed for oral disintegrating tablets (ODT). Directly compressible, tablets produced with F-Melt will disintegrate in the mouth within as little as 20 seconds and have an excellent mouth feel, claims the manufacturer. This provides the opportunity for an "On-the-go"​ delivery form that could be taken without the need for something to drink.

The company could not be contacted for further comment before the time of publication.

Mouthfeel

In addition to fast oral disintegration, F-Melt is claimed to improve the performance and mouthfeel of chewable and sublingual tablets.

Joseph Kuncewitch, Fuji’s national sales manager said: "The greatest excitement of F-Melt is that it provides the industry with the opportunity of matching a product to the active lifestyle of today's mobile consumer​."

The market for oral disintegrating tablets is a developing market and new technologies are delivering distinct advantages. But direct compression is still the preferred choice, said Fuji, because it uses conventional equipment and materials while maintaining lower manufacturing costs.

Another new excipient for the nutra industry is Fujicalin which is a directly compressible form of dicalcium phosphate anhydrous (DCPA). Fujicalin is said to be a porous and spherical material with performance that exceeds traditional DCPA. “Known for years as a problem solver, Fujicalin will enhance tablet hardness, disintegration and flowability but is best known for its ability to carry an oil active into a formulation as a dry and compressible powder​,” said the company.

Highly porous

Fuji said it has developed the technology to turn an otherwise impervious material into a highly porous, honeycombed, spherical particle which can be used for a mixture of components to target more specific applications.

For tablet formulators, this offers a way to carry an oily active into a tablet formulation, improve tablet hardness; achieve more rapid disintegration; enhance flow; and to control moisture.

For the marketing specialists, it offers new delivery forms and the ability to differentiate products or develop a line extension, said the company. It also companies to better target the point of delivery for a supplement and to facilitate increased bioavailability, it added.

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