Unigen adds antioxidants to patent store

Unigen Pharmaceuticals has been granted a composition of matter and usage patent for aloesin and aloeresin A, antioxidant aloe chromones that are contained in its Pervarin and Aloewhite commercial raw materials, writes Jess Halliday.

Suitable for oral and topical formulations, Pervarin is currently used in dietary supplements and medical foods - that is, foods available only on the recommendation of a physician to meet a patient's specific dietary need.

It contains a significant amount of aloeresin A, said Unigen's chief scientific officer Dr Qi Jia, and can support the body's endogenous antioxidation functions against damage caused by lipid peroxidation through oral or topical administration.

Regan Miles, executive vice president of Unigen told NutraIngredients-USA.com that Pervarin would also be suitable for use in functional foods, but a suitable partner has yet to be found.

Aloewhite, meanwhile, contains more than 90 percent aloesin and can be formulated into anti-aging and sun care cosmetic products.

The company said that aloeresin A, was four times more potent than the standardized green tea and grape seed extracts, three times more potent than vitamin E, even at low concentration, and stronger too than a?tocopherol and vitamin C as measured by lipid peroxidation inhibition capacity.

Aloesin is also claimed to have an oxygen radical absorbance capacity than standardized green tea and grape seed extracts.

Both Pervarin and Aloewhite have been on the market for the past 18 months.

"This utility patent will offer protection to Unigen's intellectual property and will enhance the product value for our business partners," said Jia.

The company would not disclose which companies currently market products containing the Pervarin and Aloewhite, however, as they are sold under license and Unigen's customers change the name to prevent them from becoming a commodity.

But Miles did say that he expect the patents to result in more sales of the ingredients:

"We see more and more that companies don't want to evaluate a product unless it is unique and has a patent."

Both Pervarin and Aloewhite have been under evaluation by multinational companies for almost a year, but no product launch date has yet been announced.

"My guess is that it will be in the next twelve months," he said. In January the natural ingredients supplier was granted a utility patent for its insect-derived policosanol ingredient - an announcement expected to facilitate further development of commercial products aimed at managing blood lipids and associated health concerns.