Dietary fibre - checking the evidence
on those at risk of colon cancer. Scientists re-investigating the
Wheat Bran Fiber trial have found that even for people starting on
a low fiber diet, supplements have no effect on prevention of
polyps recurrence.
A new study confirms that a high-fiber diet has no positive impact on those at risk of colon cancer.
Scientists in the US have already found in the Wheat Bran Fiber (WBF) trial, that dietary fibre does not prevent the growth of polyps in the colon. Anecdotal evidence had suggested that people who eat high-fiber diets have a lower incidence of colorectal cancer. The WBF trial compared the recurrence rate of adenomatous polyps (abnormal growths in the colon that are considered precursors of colon cancer) among people who were randomly assigned to receive a high-fiber dietary supplement (13.5 g/day) versus a low-fiber dietary supplement (2.0 g/day).
The investigators however found no difference in the recurrence rate of polyps between the two groups.
But because participants in the WBF trial consumed higher-than-average amounts of fiber compared with the general US population (17.5 grams/day versus 14.8 grams/day), some scientists suggested that these participants had adequate protection from colorectal cancer recurrence even without the addition of a high-fiber supplement. In other words, the beneficial effects of supplemental fiber might be apparent only in participants who had lower baseline fiber intakes.
To see whether this was the case, Dr Elizabeth T. Jacobs, of the Arizona Cancer Center, and her coworkers separated the participants into four groups based on their baseline fiber consumption and calculated the risk of polyp recurrence in each group. They also looked at the effect of baseline intake of fiber from specific food sources on polyp recurrence.
Baseline fiber intake did not appear to be associated with polyp recurrence. There was also no association between baseline intake of fiber from the three leading sources of dietary fiber (fruits; breads, cereals, and crackers; and vegetables) and polyp recurrence. Moreover, baseline fiber intake had no effect on polyp recurrence within each treatment group.
Full findings are reported in the the November 6 issue of the Journal of the National Cancer Institute.
